During the routine dissection of a formalin fixed Caucasian cadaver, a previously unreported variation of the sacral plexus was found in the right gluteal region. The posterior femoral cutaneous nerve was found to pierce the piriformis muscle as opposed to running along its more common course below the muscle. At the same level of the posterior femoral cutaneous nerve, the common fibular nerve also pierced the piriformis muscle, while the tibial nerve passed inferior to the piriformis muscle. No other anatomical variations were found.