Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre-operative SARS-CoV-2 diagnosis. Adjusted 30-day mortality in patients without SARS-CoV-2 infection was 1.5% (95%CI 1.4-1.5). In patients with a pre-operative SARS-CoV-2 diagnosis, mortality was increased in patients having surgery within 0-2 weeks, 3-4 weeks and 5-6 weeks of the diagnosis (odds ratio (95%CI) 4.1 (3.3-4.8), 3.9 (2.6-5.1) and 3.6 (2.0-5.2), respectively). Surgery performed ≥ 7 weeks after SARS-CoV-2 diagnosis was associated with a similar mortality risk to baseline (odds ratio (95%CI) 1.5 (0.9-2.1)). After a ≥ 7 week delay in undertaking surgery following SARS-CoV-2 infection, patients with ongoing symptoms had a higher mortality than patients whose symptoms had resolved or who had been asymptomatic (6.0% (95%CI 3.2-8.7) vs. 2.4% (95%CI 1.4-3.4) vs. 1.3% (95%CI 0.6-2.0), respectively). Where possible, surgery should be delayed for at least 7 weeks following SARS-CoV-2 infection. Patients with ongoing symptoms ≥ 7 weeks from diagnosis may benefit from further delay.

SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patients with peri-operative or prior SARS-CoV-2 were at further increased risk of venous thromboembolism. We conducted a planned sub-study and analysis from an international, multicentre, prospective cohort study of elective and emergency patients undergoing surgery during October 2020. Patients from all surgical specialties were included. The primary outcome measure was venous thromboembolism (pulmonary embolism or deep vein thrombosis) within 30 days of surgery. SARS-CoV-2 diagnosis was defined as peri-operative (7 days before to 30 days after surgery); recent (1-6 weeks before surgery); previous (≥7 weeks before surgery); or none. Information on prophylaxis regimens or pre-operative anti-coagulation for baseline comorbidities was not available. Postoperative venous thromboembolism rate was 0.5% (666/123,591) in patients without SARS-CoV-2; 2.2% (50/2317) in patients with peri-operative SARS-CoV-2; 1.6% (15/953) in patients with recent SARS-CoV-2; and 1.0% (11/1148) in patients with previous SARS-CoV-2. After adjustment for confounding factors, patients with peri-operative (adjusted odds ratio 1.5 (95%CI 1.1-2.0)) and recent SARS-CoV-2 (1.9 (95%CI 1.2-3.3)) remained at higher risk of venous thromboembolism, with a borderline finding in previous SARS-CoV-2 (1.7 (95%CI 0.9-3.0)). Overall, venous thromboembolism was independently associated with 30-day mortality ). In patients with SARS-CoV-2, mortality without venous thromboembolism was 7.4% (319/4342) and with venous thromboembolism was 40.8% (31/76). Patients undergoing surgery with peri-operative or recent SARS-CoV-2 appear to be at increased risk of postoperative venous thromboembolism compared with patients with no history of SARS-CoV-2 infection. Optimal venous thromboembolism prophylaxis and treatment are unknown in this cohort of patients, and these data should be interpreted accordingly.

Wireless Sensor Networks (WSN) is a technology that have gained a lot of importance in the last few years. From all the possible applications for WSN, target tracking is considered essential. In this application, the WSN has to determine, in a collaborative way, the trajectory of one or more targets that are within the sensing area of the network.The aim of this document is to present a collaborative algorithm based on multifrontal QR factorization for the solution of the target trajectory estimation problem with WSN. This algorithm uses a batch estimation approach, which assumes that all sensing data are available before the estimation of the target trajectory. If all the observations of the target trajectory is available, the problem can be modeled as an overdetermined system of equations Ax = b where A is sparse. This system of equations is solved by least squares method. The multifrontal QR factorization uses a tree graph called elimination tree to reorganize the overall factorization of a sparse matrix into a sequence of partial factorizations of dense smaller matrices named frontal matrices. By mapping the elimination tree into the WSN, the sensor nodes that observed the target can factorize the frontal matrices. In this manner, the WSN factorizes the matrix A in a collaborative way, dividing the work in small tasks that the sensor nodes could execute.

RESUMOEste trabalho apresenta o desenvolvimento dos algoritmos de controle de um robô móvel autônomo para coleta de lixo. O objetivo do robô é coletar latas de refrigerante espalhadas pelo chão. O sistema de navegação do robô foi implementado utilizando a arquitetura denominada "Motor-Schema". Essa arquitetura fornece um método para projetar comportamentos primitivos que atuam em forma paralela para realizar ações robóticas inteligentes em resposta aos estímulos do ambiente. O sistema de controle apresentado foi constituído por vários comportamentos primitivos que, coordenados, permitiram ao robô explorar de forma segura um ambiente desconhecido, detectar e coletar o lixo e levá-lo num depósito determinado. Os algoritmos desenvolvidos foram testados utilizando uma ferramenta de simulação 2D denominada Player/Stage. Os resultados obtidos mostraram que a solução apresentada é adequada para resolver a aplicação robótica de coleta de lixo. ABSTRACTThis work presents the control system for an autonomous mobile robot for soda can collection. The navigation system is implemented using a reactive architecture called "Motor-Schema". This architecture provides a methodology to design primitive behaviors that can act in a distributed and parallel manner to yield intelligent robotic actions in response to environmental stimuli. The control system is composed of several primitive behaviors, which enable the robot explore an unknown environment, detect and collect the soda cans and navigate toward a soda can reservoir. The algorithms are tested using Player/Stage, a software for 2D simulation. The results show that the solution is suitable for soda can collection.