Atypical and unusual locations of psoriasis are very frequent. However, localized
linear psoriasis is rare, with few cases described in the literature. It is
characterized by a linear distribution of psoriasis lesions along Blaschko lines. We
report the case of a three years old child, who presented unilateral erythematous
scaly plaques arranged along Blaschko lines in the left hemithorax, with no
associated symptoms and no lesions in other parts of the body. The differentiation of
linear psoriasis from other linear dermatoses is not easy. The combination of a
thorough history, a careful examination of the skin and histopathology are essential
to ensure the correct diagnosis and appropriate treatment.
This paper describes the association of two unusual side effects of treatment
with isotretinoin for severe acne: paronychia and excess granulation tissue in
the nails furrows. We report a case of male patient aged 19 years, who in the
course of the 36th week of treatment with isotretinoin for acne grade III showed
erythema, edema, excess granulation tissue and onychocryptosis in various nail
beds of hands and feet, with no history of trauma associated. A literature
review revealed few reports of these adverse events, and two clinical patterns
of exuberant granulation tissue has been described: one in periungual location
and other in lesions of previous acne. The rarity and lack of knowledge on the
best treatment for granuloma-like reactions make this theme a considerable
challenge.
Oculoectodermal syndrome is a rare disease characterized by the association of
aplasia cutis congenita, epibulbar dermoids, and other abnormalities. This
report describes the twentieth case of the disease. We report a 4-year-old
female child who presented with the classical features of the syndrome: aplasia
cutis congenita and epibulbar dermoids. Our case expands the clinical spectrum
of the disease to include: diffuse hyperpigmentation (some following the
Blaschko´s lines); hypopigmented skin areas on the trunk; arachnoid cyst on the
right fronto-parietal border; rounded left side of the hippocampus; and dermoid
cyst underlying the bulb-medullary transition. Our patient also reported
infantile hemangioma on the right wrist and verrucous hemangioma on the left
leg, the latter not previously described in the literature.
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