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CONTEXTO: o aumento da incidência e da prevalência da demência constituem um problema signi cativo de saúde pública, o que implica uma maior atenção às necessidades dos cuidadores familiares, sendo essencial identi ca-las. OBJETIVO: identi car as principais necessidades dos cuidadores familiares de pessoas com demência a residir no domicílio. METODOLOGIA: revisão integrativa da literatura, através das bases de dados Pubmed, Repositório Cientí co de Acesso Aberto de Portugal (RCAAP), Cumulative Index to Nursing and Allied Health Literature (CINAHL), Mediclatina e Medline, utilizando como descritores: cuidadores familiares, avaliação das necessidades de cuidados de saúde, demência e idoso. A pesquisa incluiu publicações entre 2005 e 2015, sendo identi cados 8 artigos para revisão que obedeciam aos critérios de inclusão. RESULTADOS: a análise dos dados recolhidos permitiu identi car as necessidades dos cuidadores familiares e elenca-las em três grandes grupos: i) necessidades relacionadas com o cuidador familiar; ii) necessidades relacionadas com o papel de cuidador e iii) necessidades relacionadas com o contexto do cuidar. CONCLUSÕES: foi possível identi car e reunir as necessidades destes cuidadores numa lista, o que pode servir de base para o planeamento dos cuidados dos pro ssionais de saúde e para o desenvolvimento de serviços de suporte para os cuidadores familiares.

The objective of this study is to present disaggregation coefficients for intense daily rainfalls for E2-046 rainfall station, located at Caraguatatuba, São Paulo state. The data obtained through rain gauge refer to a continuous period (31 years of series) and had a strong correlation with the measurements of the rain gauge, validating the pluviographs reading, which attributed greater reliability to the results. The average coefficient “24 hours”/“1-day” found for the study region was 1.075, which differs significantly from the values found in literature. The relative deviation considering other durations, and consequently other precipitation coefficients in relation to the mean values of the disaggregation values of the E2-046 station reached 22.06% (18 hours/“24 hours”). The relative deviation of rainfall disaggregation coefficients of the station studied in relation to the mean coefficients for the cities of São Paulo State to small durations was quite high, reaching almost 50% (10 minutes /“24 hours”). This reinforces the need of using local disaggregation coefficients.

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In 1990, the first Teratogen Information Service in Brazil (SIAT) was implemented in the Medical Genetics Service at Hospital de Clinicas de Porto Alegre. SIAT is a free-to-use information service both to health professionals and the general population, especially to women who are pregnant or planning pregnancy. The main objective of this paper is to present the activities of SIAT in its initial years (1990-2006), compared to those in the last decade (2007-2017). In addition we review the scientific contribution of SIAT in the field of human teratogenesis. Since 1990, SIAT received 10,533 calls. Use of medications were the main reason for concern, accounting for 74% of all questions, followed by other chemical exposures (occupational, cosmetics, environmental), and maternal infectious diseases. Among its main contributions to scientific knowledge was the collaboration for the identification of two new human teratogens: misoprostol in the 1990s and Zika virus in 2015/16. In conclusion, SIAT is still evolving, as is the Medical Genetics Service that hosts it. Through its 27 years of existence more than 300 undergraduate and graduate students have rotated at SIAT. Presently, SIAT is expanding the research to experimental teratogenesis and to investigation of molecular mechanisms of teratogens.