In combination, CD39, CD43, CD81, and CD95 expressions appear to be helpful to distinguish CD10 BCL, particularly BL. Phenotypic distinction between FL and GCB DLBCL remains challenging and requires further studies. © 2017 International Clinical Cytometry Society.

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Many tools exist for power analyses focused on R 2 Model (the variance explained by all the predictors together) but tools for estimating power for coefficients often require complicated inputs that are neither intuitive nor simple to estimate. Further compounding this issue is the recognition that power to detect effects for all predictors in a model tends to be substantially lower than power to detect individual effects. In short, most available power analysis approaches ignore the probability of detecting all effects and focus on probability of detecting individual effects. The consequences of this are designs that are underpowered to detect effects. The present work presents tools for addressing these issues via simulation approaches provided by the pwr2ppl package (Aberson, 2019) and an associated Shiny app.

Cylindromas are a rare benign pathology that can manifest as multiple lesions on a patient’s scalp. Standard of care is resection of lesions. We report a case of a 74-year-old man with a known diagnosis of Brooke-Spiegler syndrome which is a genetic syndrome that results in multiple recurrent cylindromas. He had approximately 70 prior resections to remove recurrent lesions with multiple grafts. After a large scalp recurrence, with multiple satellite areas, he preferred radiation to the largest site for no-surgical management. After an excellent clinical response, this led to him electing for total scalp irradiation to the remaining sites. He now has a complete response to all remaining sites.