Dao-Qun Shi scite author profile

A new acylated iridoid, valejatadoid H (1), along with fourteen known compounds, were obtained from the n-BuOH extract of the roots and rhizomes of Valeriana jatamansi, and their structures were elucidated by various spectroscopic methods.Among them, compounds 8, 11 and 13 exhibited potent inhibition on NO production, with IC 50 values of 4.21, 6.08 and 20.36 μM, respectively. In addition, compounds 14 and 15 showed anti-influenza virus activities, among which compound 14 exhibited significant effect with an IC 50 value of 0.99 μM.

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Dao-Qun Shi

Iridoids and sesquiterpenoids from Valeriana officinalis and their bioactivities

A new acylated iridoid and other chemical constituents from Valeriana jatamansi and their biological activities

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