Today the problem of correlation of mental disorders and skin diseases is relevant in Russia. Psychosomatic disorders, comorbid true acantholytic pemphigus (pemphigus) and cases of affective disorders are described on this literature review. The relationship between manifestation and exacerbations of pemphigus with psychogenic disorders is shown. Studies investigating quality of life of patients with pemphigus are described. The literature was searched in the following databases: MedLine, PubMed, Concilium Medicum, SCOPUS, Web of Science, LILACS, PEPSIC, Russian State Library, the Sechenov central science medical library.

The paper describes the relationship of psychogenic stress with the manifestation/exacerbation of pemphigus. Reviewed psychosomatic mechanisms of manifestation of pemphigus. The authors identified the relationship of clinical manifestations of pemphigus to psychogenic disorders.

The authors provide a review of current concepts of the epidemiology, etiology, pathogenesis and treatment principles for seborrheic scalp dermatitis. They also describe the results of multiple national and foreign studies confirming high clinical efficacy of ketoconazole 2% shampoo in the therapy of seborrheic dermatitis.

Psychosomatic disorders, comorbid with true acantholytic pemphigus (pemphigus) and identified clinical manifestations, the relationship of pemphigus with psychogenic disorders are described. Some patients had mental disorder (adjustment disorder) provoked by pemphigus - nozogenic reactions. In some patients with aberrant hypochondria iatrogenic (drug) hypomania was discovered on the high doses of systemic glucocorticoids. The Dermatоlоgy Index оf Disease Severity (DIDS) and The Dermatology Life Quality Index (DLQI) was calculated for all patients. According to the results of the study dissociation between the severity and the subjective perception of the disease with the help of these indicators was determined.