We here investigate the occurrence of fluoride intake-associated alterations in patients with hematologic disease on triazol antifungal medication. Clinical, laboratory, and radiology data of overall 43 patients with hematologic malignancies taking voriconazole (n ؍ 20), posaconazole (n ؍ 8), and itraconazole (n ؍ 4), and a hematologic patient control group (n ؍ 11) are described. Bone pain and radiologic evidence of periosti-
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