Objective- To assess osteosarcoma epidemiology in Haji Adam Malik General Hospital. Material and Methods- This study is a retrospective descriptive study with a crosssectional approach. Patient with musculoskeletal tumour (especially osteosarcoma) in Haji Adam Malik Hospital from January 2012 to Desember 2017 period, got their age, gender, musculoskeletal tumour type, biopsy result, tumour sites, treatment completion, metastasis and amputation status recorded from their medical record. Result-Primary bone tumors is the most cases and found in 50% of musculoskeletal tumors followed by soft tissue tumors and metastatic bone disease. Male (60%) have slightly higher prevalence than female in (40%). The incidence of primary bone tumors shows osteosarcoma, GCT, and osteochondroma are in the top three with 63%, 13%, and 6% respectively. Specifically for osteosarcoma, male and female have 1.9 : 1 prevalence ratio. The most common sites for osteosarcoma is distal the femur (45%) and proximal tibia (29%). About 63% of patients undergo complete treatment and with 55% recorded with metastasis in the first diagnosis and amputation was performed in 89% of patients. Conclusion- Primary bone tumors dominate the data with 50% for musculoskeletal tumors followed by 31% soft tissue tumors and 19% metastatic bone disease. The incidence of musculoskeletal tumors shows that men are slightly higher than women in 60% and 40%. The incidence of primary bone tumors shows osteosarcoma, giant cell tumor, and osteochondroma are in the top three with 63%, 13%, and 6% respectively.

Introduction:Osteosarcoma is a malignant neoplasm originating from poorly differentiated cells in the metaphyseal area long bones of children, with a 5-year survival rate below 20%. The evaluation of patient's prognosis with osteosarcoma using the modified Glasgow Prognostic Score (mGPS) determine the albumin and C-Reactive Protein values to assess inflammation of a tissue. The mGPS scores are 0,1,2 with the higher the score the worse the prognosis. Researchers want to know the role of mGPS in osteosarcoma patients and the prognosis of life expectancy in a general hospital. Material and Method:A retrospective cohort study with a population of osteosarcoma patients at General Hospital H. Adam Malik Medan, which was examined for albumin and C-Reactive Protein (CRP). Using the total sampling method, patients' data was obtained through hospital medical records from January 2012 to December 2017 and a mGPS assessment (0,1,2) was recorded. Then a follow-up was carried out recording patients who were found to survive at >2 years and >5 years. Results:There were 34 patients, of which 26(76%) were male and 8(24%) were female. With the highest age group in the 2nd decade (n=20, 59%) followed by the 3rd decade (n=6, 17%) and the 1st decade (n=5, 15%). The predilection for tumor location was often the same in the distal femur and proximal tibia (n=12, 35%) followed by the proximal humerus (n=5, 15%), and proximal femur (n=4, 12%). Meanwhile, the number of patients based on the mGPS 0-2 value was overal the same (n=11-12, 32-36%). In the 2-year survival rate group (p=0.033), there were 9 (45.0%), 7 (35.0%), and 4 (20.0%) patients with mGPS scores of 0, 1, and 2. Meanwhile, there were 5 (71.4%), 2 (28.6%), and 0 (0.0%) patients with mGPS scores of 0, 1 and 2 in the 5-year survival rate group (p=0.009). Conclusion:Based on the results of data analysis, it was found that there was a significant relationship (p <0.05) between the mGPS assessment and the patient's life expectancy in 2 years and 5 years.