No abstract

No abstract

Summary A new method is described for studying the modification by drugs of the oxidation‐reduction systems of the skin in man. This consists in noting the changes produced in the decolorisation time of a standard intradermal wheal made with 2:6‐dichlorophenol indophenol indicator solutions. The decolorisation time is significantly decreased by ascorbic acid and by glutathione, and increased by adrenocorticotrophic hormone and cortisone, when these agents are administered systemically. The significance of the electrode potential (Eh) of the tissues in relation to these findings is discussed.

No abstract

NATURE March 21, 1953 voL 111 is the limiting reaction in the soil and that the shape of the toxicity-time curve is a direct reflexion of the activity of the hydrolysing organism. The further conversion to acid, probably by a different organism, takes place so rapidly that the ethanol intermediate can never accumulate in amounts detectable even by the sensitive assay employed.