Both IR700 and intact cetuximab-IR700 biodistributions were consistent with known epidermal growth factor receptor (EGFR) expression, and changes between 2 and 14 days were consistent with rapid metabolism and excretion of the cetuximab-IR700.

The factors that influence the measurement of stress by the "two-exposure" X-ray diffractometer technique in the WC phase of WC-Co cermets were studied. Chromium Ka radiation was used on the (1072) line of WC (20=135.8"). The X-ray values of Young's modulus and Poisson's ratio are 105x10' psi and 0.19, respectively, and the X-ray stress factor is 1.51 X 10' psi/A. The measured stresses are biaxial. Because penetration is limited to less than 5 pm for CrKa radiation, extreme care in surface preparation and heat treatment is required. A suitable preparation is metallographic polishing with 6 pm diamond followed by annealing in hydrogen at 750°C. This treatment allows measurement of about 40,000 psi compressive temperature stress inherent in the WC particles resulting from differences in coefficients of thermal expansion between WC and Co. Mechanical stresses can also be measured; they arise from external forces such as grinding, polishing, and sand blasting. Mechanical and temperature stresses cannot always be clearly distinguished, however.

ABSTRACT. Thermal considerations affecting the rate of formation of sea ice are discussed showing the effects of the major variables. The natural solidification process (freezing downward from contact with cold air) is contrasted with freezing of layers cast on the surface of sea ice. Transient heating and cooling of solid ice during and after flooding are analyzed. Procedures for maximizing the rate of ice formati on and minimizing base-ice heating are discussed , along with factors affecting brine segregation. REsuME. Les auteurs discutent Ies facteurs thermiques susceptibles d'agir sur la vitesse de formation de la glace de J'eau de mer et signalent le role des variables les plus importantes. Le processus nature! de la solidification-au cours duquella congelation se fait du haut vers le bas par suite du contact avec l'air froid -est compare avec la congelation de nappes d'eau artificiellement creees a la surface de la glace de-mer. Le rechauffement et le refroidissement transitoires des couches solides de la glace soumise a cette inondation sont analyses. Les auteurs suggerent des methodes pour accelerer au maximum la formation de la glace et reduire au minimum le rechauffement de la glace sous-jacente, et discutent les facteurs qui determin ent la segregation d'eau a salinite elevee pendant la congelation.ZUSAMMENFASSUNG. Thermische Bedingungen, die die Geschwindigkeit beeinflusscn, mit der sich das Meereis bildet, und die Einwirkungen der Hauptvariablen darauf werden besprochen.

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