No abstract

Using the general procedure of Cason,16 43.7 g. (0.23 mole) of 8-cyanooctanoyl chloride and dimethylcadmium [prepared from 0.5 mole of methylmagnesium bromide and 50 g. (0.27 mole) of cadmium chloride] were allowed to react and gave 27.0 g. of crude product, b.p. 130-135°( 2 mm.). Fractionation through a one meter Podbielniak column separated this crude material into 2.5 g. of 2,10-hendecandione, b.p. 132-134°( 4 mm.), and 23.5 g. (61%) of 9-ketodecanenitrile. After crystallization from methanol, the 2,10-hendecandione melted at 61.8-62.3°( reported18 m.p. 65°) and formed a disemicarbazone melting at 183-184°( reported16 m.p. 184°). The 9-ketodecanenitrile was refractionated and boiled at 161-162°( 9-10 mm.); »26d 1.4430. Anal.

No abstract

No abstract

No abstract