These data indicate that a condition characterized by sympathetic predominance may favour the development of sustained hypertension and hypercholesterolemia early in life, and lead to increased susceptibility to vascular complications. They further indicate that the increased white-coat effect is not an innocent phenomenon.

Indexes of arterial distensibility are impaired in the white-coat hypertensive group and similar to those in the sustained hypertensive group, indicating that early changes in the arterial wall can occur in white-coat hypertension. This may account for the higher risk of stroke that has been described in this condition.

Vaccination against SARS-CoV-2 will likely be the most promising way to combat the pandemic. Even if mass vaccination is urgent, it should still always be supported by appropriate patient safety management. The aim of this study, based on failure mode, effects and criticality analysis (FMECA), was to identify possible failures and highlight measures that can be adopted to prevent their occurrence. A team of resident doctors in public health from the University of Padua and specialists in risk analysis in public health examined the mass vaccination process. A diagram was drafted to illustrate the various phases of mass vaccination, analyze the process, and identify all failure modes. Criticalities were ascertained by rating the severity, frequency and likelihood of failure detection on a scale of 1 to 10. We identified a total of 71 possible faults distributed over the various phases of the process, and 34 of them were classified as carrying a high risk. For the potentially high-risk failure modes, we identified 63 recommended actions to contain the cause of their occurrence or improve their detection. For the purpose of detecting potential failures, FMECA can be successfully applied to mass vaccination, which should be considered a high-risk process.

These data show that the SAA-102 device satisfies ESH, AAMI, and BHS protocols for both SBP and DBP and may be recommended for everyday use for BP monitoring at home and in clinical practice.

The objective of this study was to determine the accuracy of the UEBE visomat comfort eco blood pressure measuring device tested according to the requirements of the International Protocol of the European Society of Hypertension. The device evaluation was performed in 33 participants with a mean+/-SD age of 54.3+/-18.7 years (range 30-91 years). Their systolic blood pressure (SBP) was 144.0+/-23.7 mmHg (range 100-180 mmHg), diastolic blood pressure (DBP) was 86.2+/-14.4 mmHg (range 60-110 mmHg), and upper arm circumference was 29.4+/-2.8 cm (range 24.0-34.0 cm). Blood pressure measurements were performed in the sitting position. The visomat comfort eco passed all three phases of the European Society of Hypertension protocol for SBP and DBP. Mean blood pressure differences for the visomat comfort eco (device-observer) were -0.5+/-5.7 mmHg for SBP and -1.4+/-5.3 mmHg for DBP. In conclusion, the present results show that the UEBE visomat comfort eco monitor can be recommended for clinical use in the adult population.