Objectives. What are the Predictors of Intracranial Aneurysm (IA) Rupture based on angiographic findings among patients in Indonesia’s Population Based on Angiographic Findings. Materials and Methods. We conducted a cross-sectional study on subjects with IA not caused by congenital aetiologies or other vascular malformations with cerebral angiography performed from January 2017 to January 2021. Demographic data and aneurysm profile, which include aneurysm count, size, location, and rupture event, were collected. The correlation between risk factors and IA rupture events was determined using bivariate and multivariate analysis. Results. From 100 angiography data (33 males and 67 females), the mean subject age is
51.94
±
10.78
. We observe a total of 121 IAs from all subjects. Most of the IAs are in the anterior circulation (104 aneurysms, 85.96%), have small size (77 aneurysms, 63.64%), and are found in ruptured conditions (90 aneurysms, 74.38%). Males have a greater aneurysm count (
1.36
±
0.74
vs.
1.13
±
0.55
,
p
=
0.036
) and larger aneurysm size (
p
=
0.002
). Aneurysm size is significantly correlated with its location (
p
=
0.008
). Medium size (
p
=
0.019
; OR 2.62, 95% CI 1.08-6.36) and location other than the internal carotid artery are associated with increased rupture event. Multivariate analysis revealed that gender (
p
=
0.031
; aOR 5.37, 95% CI 1.17-24.70) is a significant risk factor of IA rupture event. Conclusion. IA profiling will enable clinicians to determine the risk of rupture and treatment plans for the Indonesian population. Further studies with a larger sample size are required to confirm these findings.
Pemerintah daerah memiliki kewenangan dan kemandirian untuk mengatur urusan pemerintahan daerah dalam rangka menjalankan pemerintahan daerah. Masing-masing daerah dalam menyelenggarakan urusan pemerintahan yang menjadi kewenangannya berhak untuk membuat kebijakan baik dalam rangka peningkatan pelayanan maupun dalam rangka meningkatan peran serta masyarakat dalam pembangunan daerah. Salah satu unsur penting dalam implementasi proses tersebut adalah melalui pembentukan peraturan daerah. Corporate social responsibility merupakan salah satu materi yang diatur dalam peraturan daerah di berbagai daerah di Indonesia, meskipun sudah ada Putusan Mahkamah Konstitusi Nomor 53/PUU-IV/2008 yang menyatakan bahwa pemerintah daerah tidak berwenang untuk membentuk peraturan daerah Corporate social responsibility. dalam membuat peraturan daerah, pemerintah harus memperhatikan syarat - syarat yaitu wewenang, subtansi, dan prosedur. Apabila syarat - syarat tersebut yang dimaksud tidak dipenuhi maka berakibat peraturan daerah yang dibuat tidak sah. Ketika peraturan daerah yang dibentuk tidsak sah maka dapat diajukan pembatalan kepada Mahkamah Agung (jucial review). Sehingga ketika terjadi pembatalan peraturan daerah maka berakibat bahwa peraturan daerah tersebut tidak mengikat lagi.
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