e-Health adoption in health care leads to a clinical transformation, affecting the scope of health data, work processes, roles, interactions, and above all, the culture of the global health system as a whole. Advancements in the application of health information technology (HIT) have certainly reformed the health care landscape and how health data are being documented, processed, and disseminated This review paper aims to explore the expanding scope and functions of health information management in e-health. The study also intends to identify the evolving functions of health information management for the meaningful use and transmission of health data in e-health environment. The study reveals the challenges of transmitting health data in the e-health systems and the areas of e-health where meticulous health information management is required.