Background: Use of tobacco is 2nd major cause of death in the world. The use of tobacco will be responsible for 10 million deaths per year by 2020-2030, mainly in China and India. India rank 4th in total tobacco consumption in the world. The prevention of tobacco use in young Indians appears as the single greatest opportunity for preventing non-communicable disease. The objective was to study knowledge, attitude and practice of tobacco consumption among male college students of rural area of PuneMethods: Present cross-sectional study conducted among male college students of rural field practice area of a medical college during September to October 2015. The students were interviewed with prestructured questionnaire and investigator had explained all the details. The data was tabulated and analyzed using MS excel and SPSS.Results: Total 207 male college students with mean age 18.6±1.2 years were enrolled. 162 (78.3%) students have good knowledge of tobacco consumption effects whereas 191 (92.3%) have favorable attitude towards tobacco consumption. Among study subjects, 26 (12.6%) were consuming tobacco in one and or the other form. Out of these, 15 (57.7%) were smokers. Mean age of initiation of tobacco consumption was 16.9±1.9 years. The knowledge (p=0.034) and attitude (p=0.007) were significantly associated with education of students. The gap between knowledge and practice was also significant (p=0.01).Conclusions: The study suggests though the knowledge of students toward tobacco consumption is adequate, tobacco consumption habit is higher in students. This gap can be reduced by proper counseling of the students.