Background: Liposarcomas are uncommon malignant mesenchymal tumours arising in the extremities and sometimes in the retroperitoneum.
Methods: We discuss a case of a rare sigmoid colon liposarcoma in a lady who presented with constipation and tenesmus.
Results: In the case of a large liposarcoma, it is difficult to maneuver the mass without the risk of serosal tears. As we make an attempt in minimally-invasive surgery for this patient, we decided that it would be useful to utilize endoscopy to help reduce the mass and attempt to resect the mass laparoscopically without extensive serosal tears.
Conclusion: A hybrid endoscopic-laparoscopic high anterior resection can help to manipulate the large tumour and avoid a low anastomosis, thereby reducing the risk of an anastomotic leak when compared to a higher anastomosis.
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