[thiazolium-2,2 0 -14 C 2 ]-SAR97276A, a bis(thiazolium) antimalarial development candidate, was synthesized from [ 14 C]-thiourea with an overall radiochemical yield of 15%. The synthetic route involves a modified procedure for the synthesis of [ 14 C]-sulfurol, also a key intermediate in thiamine synthesis, which was developed due to unlabelled chemistry proving irreproducible with the radiolabelled substrate.
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