RAP is a common complaint of childhood with associated familial, psychological, and co-morbid conditions. Epidemiologic studies of RAP in children may offer information on the evolution of functional bowel disorders through the lifespan.

Background-IBS is a common disorder that occurs in adults. The natural history of symptoms and risk factors that contribute to IBS may begin in the childhood period. The aim of this systematic review of the published medical literature was to determine what early life factors have been demonstrated to contribute to the development of IBS in adolescents and adults.

No abstract