Abstract-Medical waste is directly or indirectly infectious, toxic and other hazardous waste, and high-temperature steam sterilization is a widely used non-incineration technology for centralized treatment medical waste. Basing on the analysis of flow chart of medical waste hightemperature steam treatment, the specific contents of medical waste high-temperature steam treatment technology process, and the graph of high-temperature steam sterilizer pressure or temperature changing with time, the key problem of heat penetration time in high-temperature steam sterilization technology is pointed out, and the problems caused by the undetermined heat penetration time are analyzed. Medical waste is moisture porous media and it has the properties of porous media that interaction interphase, structural diversity, multi-scale, distribution randomness and so on, the research on porous media calorific value heat transfer has made tremendous progress. At last, concluded that conducting research on the heat and mass transfer mechanism of high-temperature steam in medical waste porous media can provide a scientific basis for reasonably determine the heat penetration time.

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