The paper presents the results of the development of separate technological operations and equipment for the technological operations of the technological process of production of Lutetium trichloride-177 on the basis of JSC «Institute of Reactor Materials» with a specific activity of 1 TBq/mg by means of an activation method by irradiating neutrons in the IVB-2M reactor with a starting material containing isotopically-enriched lutetium-176 and subsequent radiochemical processing. The Lutetium-177 radionuclide is one of the most promising β-emitting radionuclide, which can become a leading material in radionuclide therapy of oncological diseases. The paper focuses on the technological aspects of the production of Lutetium-177 trichloride, the readiness of the proposed technological and control operations for regular use. New technological equipment has been developed and tested ensuring the implementation of technological operations within the process in manual and automated modes. To control and document all stages of production in accordance with the requirements of Quality Assurance System and Good Manufacturing Practice, a new automated system has been developed for recording process parameters, documenting and maintaining the life cycle of Lutetium-177 trichloride, which provides collection and storage of textual, graphic and multimedia information about all stages and operations of production, data analysis, and the formation of a package of documents for the transfer of Lutetium-177 trichloride to the consumer. This system combines a centralized database-a database server, a set of electronic computers with specialized software and production equipment, participating directly in production at 10 production workplaces, as well as the workplace of the technology administrator responsible for the quality and warehouse.

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The work deals with the problems of a self-development organization considered as a self-organization system without hierarchy and employee position. Such kind of management is realized by self-management teams having full authority, responsibility and focus on the result. An individual and group motivation mechanism uses the employee potential to achieve one’s ambition targets. The employee and one’s potential are engaged with a maximum power in all fields of activity. Enterprises management explores employee engagement to estimate and manage this process. Each manager has enough cases when employee goes far beyond job responsibilities to achieve the result. This employee is engaged taking an initiative and informal responsibility. Engagement is a multidimensional construction, which demonstrates employee wishes to invest self-resources (knowledge, skills, competences, emotions and power) in enterprises activity. Engagement is a positive moment implying active involvement, loyalty and direct work. A lot of engagement investigations are aimed at management, result and employee’s participation in organization management. The study of employee’s initiative is a part of employee’s engagement according to infrastructure and information factors at industrial enterprises in Perm region described in the article.