This article gives historical overview of the development of international and European dermatovenereological societies. The first European Dermatological Society and the first world Venereological Society open in Russia. Taking into consideration the fact that it was the first officially registered national dermatological society whereas Municipal Society of New York and American National Society were not registered by state authorities, the Russian Society is regarded here as the first world official dermatological society. This article reviews the proffesional development of Prof Benjamin Mikhialovitch Tarnowsky (1837-1906) the most significant dermatovenerologist, influenced the development of world and Russian dermatovenerology, worked in the first world hospital specifically devoted to venereology, Kalinkinskaya Hospital ( founded in 1750, Saint Petersburg). Depicts XII International Congress, held in Moscow in August 7-14th, 1897, where the dermotology section was represented by internationally recognized scientists. Among speakers Kaposi (Wien), Hallopeau (Paris), Gaucher (Paris), Barthelemy(Paris), Wolf (Strassburg), Rosenthal (Berlin), Nikolsky (Kiev), Lindstrem (Kiev), Jullien (Paris), Poper- Mor (Budapest), Schwimmer (Budapest), Pospelov (Moscow), Tarnowsky( Saint Petersburg); such sientists as Unna, Campana, Lassar, Soffiantini, van Hoorn, Vatrashevsky, Yakovlev, Sack participated in the discussion.

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Erythroderma remains a condition difficult to study and treat. We showed that a correct judgment about its cause can be based on objective histopathological criteria in up to 60% of cases. More studies are needed to try to find out further histological and/or immunohistochemical markers that could help the clinician with the erythroderma etiology diagnostic process.

The differential diagnosis between lichenoid drug eruption (LDE) and lichen planus (LP) is difficult due to similar clinical and histological signs but important for treatment and prognosis. The purpose of this study was to propose the new diagnosis method for differentiate LDE from LP. During 2015-2018, 20 patients with confirmed LDE, 13 patients with LP and 134 controls were examined and treated at the Lenoblcenter. All enrolled patients were underwent the injection of 0.5 mL of the 2% lidocaine solution by insulin syringe into the papule with following histological examination. The formation of a blister (bulla) at the site of injection was considered a positive test result. Among LDE, 18 of 20 patients were found positive for developing blister (bulla) and two results were questionable. In 12 of 13 LP patents, bulla on the site of injection was not identified and the result of one patient was nonspecific. All

В статье представлена современная концепция лечения синдрома Сезари, выбор оптимального терапевтического алгоритма, а также случай собственного наблюдения.