Aim: This paper describes some limnological variables of four reservoirs with different trophic status (Billings, Guarapiranga, Jundiaí and Paiva Castro) of the Metropolitan Region of São Paulo, Brazil, aiming to characterize the water quality in these reservoirs. Methods: Water sampling occurred between October 2011 and September 2012, on subsurface, at the pelagic compartment. Physical and chemical characteristics of water were evaluated, and the Trophic State Index (TSI) was calculated. Multivariate Principal Components Analysis (PCA) was used to ordinate sampling sites and periods in relation to environmental data. Results: Two reservoirs were classified as eutrophic (Billings and Guarapiranga), one as mesotrophic (Jundiaí) and one as oligotrophic (Paiva Castro). The highest concentrations of total phosphorus, nitrogen and chlorophyll a were recorded in the eutrophic reservoirs. The lowest values of dissolved oxygen concentration were registered at Guarapiranga reservoir. Residence time in Paiva Castro reservoir was very low (one day); on the other hand, the highest value was recorded in Billings reservoir: 428 days.

ResUmoObjetivo: Revisar os conhecimentos existentes em relação ao uso de fatores de crescimento epidérmico e estimulador de colônias de granulócitos na prevenção e/ou no tratamento da enterocolite necrosante (ECN) durante o período neonatal. Fontes de dados:Revisão da literatura, nas bases de dados Medline, Lilacs, SciELO e PubMed, utilizando os unitermos "recém-nascidos", "enterocolite" e "fatores de crescimento", no período de 2003 a 2007. Nesta busca, 49 artigos foram encontrados, sendo 17 pertinentes ao tema. Também foram utilizados outros artigos, independente do ano de publicação, relacionados a aspectos definidores da ECN no recém-nascido.Síntese dos dados: A ECN continua sendo responsável por uma elevada morbimortalidade neonatal. Os mecanismos fisiopatológicos vêm sendo elucidados e, a partir deles, são discutidas novas terapias, como o uso de fatores de crescimento, destacando-se o fator de crescimento epidérmico e o fator estimulador de colônias de granulócitos.Conclusões: O uso de fatores de crescimento no tratamento e prevenção da ECN neonatal parece promissor. É necessário maior número de ensaios clínicos para comprovar sua eficácia e segurança. Enquanto isso, a melhor prática médica continua sendo a prevenção da doença.Palavras-chave: recém-nascido; dietoterapia; fatores de crescimento; enterocolite necrosante. Data sources: Literature review of Medline, Lilacs, SciELO and Pubmed databases, using the key-words "newborn", "enterocolitis" and "growth factors", from 2003 to 2007. Fourty-nine papers were retrieved, but only 17 related to the subject. Other studies that described some clinical aspects of enterocolitis were also included, regardless of the year of publication.Data synthesis: Necrotizing and enterocolitis has been an important cause of morbidity and mortality in the neonatal period. As the knowledge about the pathophysiology of this disease improves, new therapies, such as the administration of epidermal growth factor and granulocyte colony-stimulating factor, are being discussed.Conclusions: The use of growth factors for treatment and prevention of NEC seems promising. However, further clinics assays are needed to evaluate the effectiveness and the safety of these growth factors. At this moment, the best clinical practice is the prevention of the disease.Key-words: infant, newborn; diet therapy; growth factors; enterocolitis, necrotizing.