Dexamethasone and memantine were found superior to piracetam in reducing apoptosis due to cisplatin ototoxicity. Further studies of this subject are needed, incorporating electron microscopy and auditory brainstem response testing.

The present study demonstrates accelerated functional recovery associated with etanercept treatment after facial nerve crush injury in rats.

Both BC and PORP are reliable and efficient methods for the repair of incudostapedial joint defects. There is no difference between these 2 methods, based on the hearing results. Additional research is necessary to determine the maximum incudostapedial defect length suitable for bone cement repair.

Amaç: Bu çalışmada hastaların otoskleroz cerrahisi sonrası işitme sonuçları ve işitsel başarı oranları değerlendirildi ve cerrahi komplikasyonları ve tedavileri irdelendi. Objectives: In this study we aimed to evaluate the audiologic results and audiologic success rates following otosclerosis surgery and to discuss surgical complications and their management. Results: Functional success was achieved in 105 of 115 operated ears (91.3%). Functional success rates according to types of piston for 0.6 mm wire Teflon piston (n=71), fluoroplastic Teflon piston (n=30), K piston (n=12) and Easy piston (n=2) groups were, 88.7%, 93.3%, 100%, and 100% respectively. Six patients (5.2%) underwent revision surgery. Hastalar ve Patients and Methods Conclusion:Our study results suggest that stapes surgery is a successful and safe treatment modality with high success and low complication rates in the management of otosclerosis.

ObjectivesHealing processes of the nose and paranasal sinuses are quite complex, and poorly understood. In this study, we aimed to compare the effect of mucosal autologous grafts on the degenerated rabbit maxillary sinus mucosa with spontaneous wound healing. It is hypothesized that mucosal grafts will enhance ciliogenesis and improve the morphology of regenerated cilia.MethodsTen female New Zealand rabbits were included in the study. They underwent external maxillary sinus surgery through a transcutaneous approach. A total of 20 maxillary sinuses were randomly divided into 2 groups: ‘spontaneous healing group’ and ‘autologous graft group.’ The animals were sacrificed at the 14th day after the surgery. Scanning electron microscope (SEM), and light microscope were used for the evaluation.ResultsCellular composition of the graft group is better than the spontaneous healing group. The graft group had larger areas covered with ciliary epithelium than the spontaneous healing group, and the mean length of the cilias were also longer. Additionally, there were wider cilia with abnormal morphology areas in the spontaneous healing group.ConclusionIn our opinion, covering of the denuded areas with a graft improves re-epithelization, and may prevent the early complications after sinus surgeries.