The evolution of knowledge in the areas of innovation and sustainability arises from a dynamic process of consolidation of concepts and theories in academic research around the world. In this context, the present article aims to analyze the scientific production of articles related to innovation and sustainability, through the analysis of semantic networks. A quantitative, exploratory, bibliometric, longitudinal methodology was used, adopting the analysis of semantic networks to, through the metric betweenness centrality establish standards and trends of complete scientific documents. The database used consists of 1054 complete articles from the Web of Science database. The results indicate possible contributions of the research in two main aspects. The first is theoretical, where the results of the research help the exploration of the studied area over time. The second strand is practical, since the methodology used can be an important tool to understand an extensive and complex scientific area.