Aqueous solutions of the polymer poly(vinylpyrrolidone) (PVP) were analyzed in terms of surface tension (Wilhelmy-Plate), density (vibrating tube density meter), and dynamic viscosity (falling ball viscometer) for different molar masses, concentrations, and temperatures. Surface tensions were determined for PVP 10, K25, and K90 at 298.15 K. Densities and viscosities were studied with PVP K25 and K90 in a temperature region from (293.15 to 310.15) K. The dynamic viscosity isotherms were fitted successfully to a basic polynomial function. The experimental data are discussed and compared to literature data.
Experimental solubility data of the nonsteroidal anti‐inflammatory drugs (NSAIDs) ibuprofen, salicylic acid, and naproxen as well as of the plant‐derived active component phytosterol have been determined in aqueous stabilizer solutions as a function of stabilizer concentration. SDS, Solutol® HS15, Tween® 20, Tween® 80, polidocanol, Lutrol® F68, PVP 10, PVP K25, and PVP K90 were chosen to solubilize the drugs. Furthermore, the influence of temperature, buffer, and pH value of the aqueous solution on drug solubility was investigated.
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