A simple, inexpensive method for the synthesis of deuterated diphenylhydantoin is described. moiety of the diphenylhydantoin molecule. Ten deuterium atoms a r e introduced to the 5,5-diphenyl KEY WORDS Deuterated diphenylhydantoin; Mass fragrnentographic analysis Vol. X , 469 (1974). Division of Medicinal C h e m i s t r y and Pharmacognosy:: and Division of P h a r m a c e u t i c s and P h a r m a c e u t i c a l Analysis>::< Lexington, Kentucky 40506 University of Kentucky, College of P h a r m a c y t T o whom correspondence should be a d d r e s s e d .
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