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Background Periodontitis is a chronic inflammatory disease characterized by progressive damage on the structure of tooth-supporting tissues. The aim of the study is determining the combination photodynamic effect of diode laser 405 nm treatments and the administration of doxycycline 0.1% within 1, 3, 5, and 7 days on a Wistar rat model of periodontitis. Methods Samples were induced with Porphyromonas gingivalis ATCC33277 to allow periodontitis development and were treated with combination of doxycycline and laser diode, then statistical analysis was carried out (One-Way ANOVA test and the post-hoc Duncan test; Kruskal–Wallis test and Mann–Whitney follow-up test for non-parametric data). Samples were divided into five groups, laser exposure used was 405-nm diode laser with energy density of 8 J/cm2. The expression level of histomorphometric was calculated by measuring the number of macrophages, lymphocytes, fibroblasts and the distance between the CEJ-AV. Results The results showed that the combination treatment of doxycycline and laser exposure yielded immunomodulatory effects. The expression level of fibroblast and the distance between CEJ-AV bone showed that the combination of doxycycline and laser therapy exerted healing effect in rat models of periodontitis on day 5 and 7. Conclusion The combination of doxycycline 0.1% and diode laser therapy provides a healing effect in rats models of periodontitis.

Purpose This study aims to examine the effects of red 649 nm 4 J/cm2 and blue 403 nm 8 J/cm2 diode laser treatment for post-extraction wounded healing in rats through histopathological and immunohistochemical analysis. Methods Samples of 54 Wistar rats were divided into six groups: C- control group without treatment; C + wounded group without treatment; TB wound group with Povidone-iodine treatment; TD wounded group with doxycycline treatment; TLB wounded group with 403 nm diode laser treatment; and TLR wounded group with 649 nm diode laser treatment. Mandibular samples were observed for the number of lymphocytes and fibroblasts cells, new blood vessels formation, Interleukin 1β, and Collagen 1α expression level. Results Based on the histopathological test results, red laser diode treatment significantly increased the number of lymphocyte, fibroblast cells and the formation of new blood vessels. Meanwhile, immunohistochemical tests showed an increase in the expression of the Colagen-1α protein which plays a role in the formation of collagen for new tissues formation after damage, as well as a decrease in Interleukin-1β expression level. Blue laser is also able to show a positive effect on wound healing even though its penetration level into the tissue is lower compared to red laser. Conclusion The red diode laser 649 nm has been shown to accelerate the process of proliferation in wound healing post molar extraction based on histopathological and immunohistochemical test results.

Kontes Robot Sepak Bola Indonesia (KRSBI) is an annual event for contestants to compete their design and robot engineering in the field of robot soccer. Each contestant tries to win the match by scoring a goal toward the opponent's goal. In order to score a goal, the robot needs to find the ball, locate the goal, then kick the ball toward goal. We employed an omnidirectional vision camera as a visual sensor for a robot to perceive the object's information. We calibrated streaming images from the camera to remove the mirror distortion. Furthermore, we deployed PeleeNet as our deep learning model for object detection. We fine-tuned PeleeNet on our dataset generated from our image collection. Our experiment result showed PeleeNet had the potential for deep learning mobile platform in KRSBI as the object detection architecture. It had a perfect combination of memory efficiency, speed and accuracy.

This study aims to determine the effectiveness of the antimicrobial photodynamic therapy (aPDT) LEDs of 392 nm and 628 nm red LEDs for photoinactivation on Staphylococcus aureus in vitro and the photodynamic effectiveness of therapy for wound healing in mice in vivo. The sample used was Staphylococcus aureus bacterial isolate which was infected on mice incision wounds. The LED exposure was carried out at the energy density of 19.44 J/cm2, respectively. In vitro test samples were divided into three groups, namely (P0): control group, (P1): LED treatment group 392 nm, (P2): LED treatment group 628 and (P3): LED combination treatment group 392 and 628 nm. In the in vivo test, the mice of infectious wound models were divided into 5 namely (M+): positive control group, (M-): negative control group, (M1): LED treatment group 392 nm, (M2): LED treatment group 628 and (M3): LED combination treatment group 392 and 628 nm. The results of in vitro studies showed an increase in the photoinactivation effect on LED exposure, with the effectiveness of inactivation on the LED 392 nm at 67.10%. The effect of photoinactivation of bacteria on wounds in vivo due to photodynamic therapy in the red LED exposure group was 88%, blue LED exposure group was 94%, exposure combination group of red and blue LEDs was 95%. So, the antimicrobial photodynamic therapy LEDs are effective for bacterial inactivation and accelerate wound healing in mice.