To cite this article: Iqbal, A. et al. (2018). Synthesis and characterisation of rice husk ash silica drug carrier for α-mangostin.

Apart from being the primary source of food to other living things, plants also have medicinal value to treat various kinds of diseases. In recent years, it has been proposed that the extract from plants may be used as natural antioxidants which can help to prevent the generation of carcinogens in human body. In addition, plants also have antimicrobial agents to inhibit the growth of pathogenic microbes. This study was intended to investigate the antioxidant properties and antimicrobial activity of methanolic extract of Tinospora crispa stems extracted using soxhlet extraction method. The antimicrobial properties of T. crispa stems extract were tested using disc diffusion method against Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 11778, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Candida albicans IMR C S23/11 A and Saccharomyces cerevisiae IMR S 617/068. The antioxidant properties of the extract were investigated by using Total Phenolics Content (TPC), Total Flavonoids Content (TFC), DPPH free radical scavenging and b–carotene bleaching assays.  The TPC value was 6.12 g GAE/100 g of dried extract while the TFC value was 55.58 g QE/100 g of dried extract. The IC50 of DPPH scavenging assay for the extract and ascorbic acid were 0.21 and 0.04 mg/mL, respectively. The average percentage of b–carotene bleaching assay was 38.3 % as compared to BHT, which was 45.1%.  The disc diffusion method showed no inhibition zone against all the strains of microorganisms at all concentrations of the extracts (0.5, 1.0, 2.5 and 5.0 mg/disc).

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Introduction: Flaxseeds offer a wide range of pharmacological properties including antioxidant, antibacterial and anticancer. However its effect on mesenchymal stem cells has not been elucidated. Thus, this study aimed to determine the effects of flaxseed crude extract on stem cell from human exfoliated deciduous teeth (SHED) in terms of cell viability, morphology and proliferation activity. Materials and Methods: Whole flaxseeds were ground and extracted with absolute ethanol using soxhlet extractor. The effects of flaxseed on SHED were assessed for cell viability using MTT assay, cell morphology using inverted microscope and proliferative activity describe as population doubling time (PDT) using alamar Blue assay. Fatty acid composition of flaxseed was analysed using gas chromatography-mass spectrometry (GCMS) instrumental technique. Results: The effects of flaxseed on SHED were observed to be dose-dependent, where higher concentration of the extract resulted in lower cell viability. The concentration of the flaxseed required to inhibit 50% of cell viability (IC50) was 10.56±0.22 mg/ml. Morphological observation demonstrated that flaxseed altered the cell morphology at concentration above 8 mg/ml. Based on alamarBlue assay, SHED treated with flaxseed at concentration 0.5, 1, 2, 4, 8, 10.56 mg/ml showed no significant difference of PDT when compared to control (p>.05). GCMS analysis revealed the presence of linolenic acid as major compound, linoleic acid and palmitic acid and oleic acid. Conclusion(s): Crude extract of flaxseed at concentration below 8 mg/ml may be applied in the future study of SHED. The linolenic acid in flaxseed may have been responsible for the cell viability and proliferation activity of SHED.

at September 15 th , 2021. The seminar under the theme "Chemistry Resilience and Continuity in the Covid-19 Pandemic".The aim of the seminar is to explore and develop the concept of learning, innovation and competence building as a chemistry education framework. The objective of ISCE is to stimulate the establishment of knowledge based strategies or teaching development in Senior High School and College. The idea of the seminar is to bring together interesting issues about what is going on ASEAN countries, School, university and to share experience regarding methodology of design thinking in teaching area.Topic of interest to be covered in the conference includes, but not limited to: 1. Chemistry education curriculum and policy 2. Teacher learning and education (in-service and pre-service teachers) 3. Environmental and social issues in chemistry 4. Assessment and evaluation 5. Independence learning and digital learning 6. Skill oriented and instructional learning in 21st century 7. Classroom action research in sciences 8. Environmental chemistry and its aspects 9. Renewable and sustainable energy 10. Materials and advance materials 11. Green chemistry, chemical engineering and chemical process This program and abstracts book provides some information concerning the schedule, list of presenter and poster presenter. Hopefully, this book helps the participants for intensively listen and get valuable information in the conference.The scientific program of ISCE 2021 comprises the following: Keynote speakers 6 papers Invited speakers 5 papers Total papers for oral presentation 56 papers Total papers for poster presentation 25 papers Total papers 92 papers iii Chairperson's Foreword Dear Participants, Friends and Colleagues, Assalamu'alaikum Wr. Wb.It is a great pleasure for me to have your participation in an online 4th International Seminar on Chemistry Education, held by Chemistry Department, Universitas Islam Indonesia. This seminar is a kind of academic activity and tradition in our department which intended to bring opportunity to all lecturers, researchers and students from all around the world. The conference aims to stimulate our participants to explore the latest development and innovation including latest instrumentation, recent applications and assessment of future commercial trends and opportunities. As we know that science and technology including chemistry and chemical industries are developing fast at recent years, so it requires the highlights on chemistry research, and moreover, it will be closely related with chemistry education sector. In other side, pandemic covid-19 changes everything including how the education being delivered. Explorations on many adaptable teaching-learning modes as well as the updating recent progresses in chemistry, chemical and chemistry education research are important. This webinar is one of the efforts, and in addition, an energetic and dynamic scientific gathering especially with all participants respected presence.As similar with previous seminar, this webinar will compi...