The serum paraoxon hydrolyzing activities in a Canadian population were bimodally distributed and interethnically variable. A clear separation between the two phenotypes was obtained by determining the ratio of activity in the presence of 5 × 10−3 M CaCl2 plus 5 × 10−1 M NaCl over that in 5 × 10−3 M CaCl2 alone. The data strongly suggest that the crucial discriminatory role was played by Ca2+.
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