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Background: Keloid is an abnormal wound healing process that extends beyond the site of injury. Keloid and tumor’s shared similarity of recurrence suggesting a shared underlying mechanism that involves stemness. Octamer-binding transcription factor-4 (Oct-4) and aldehyde dehydrogenase-1 (ALDH1) are stem cell stemness markers. This study aimed to analyze Oct-4 and ALDH1 expressions in keloid tissues.Methods: Samples were obtained from keloid tissue excisions from three keloid patients and post-circumcision preputial skin from three healthy donors (normal control) in accordance with the local ethical committee regulation. Total RNA was isolated using TriPure Isolation kit (Ameritech), and expressions of Oct4 and ALDH1 mRNA in keloid and preputial skin were determined by quantitative reverse transcription–polymerase chain reaction (qRT-PCR) using Livak method.Results: The qRT-PCR analysis revealed the expressions of Oct4 and ALDH1 in keloid and preputial skin tissues. Keloid tissues exhibited lower expression levels of Oct-4 and ALDH1 than the preputial skin. The difference was statistically insignificant.Conclusion: Keloid tissues express Oct-4 and ALDH1 as stemness markers, and the stemness characteristics of keloid might be similar to a normal skin.

Objective: This study evaluates the critical factors affecting COVID-19 vaccine acceptance in Indonesia using a proposed extended theory of planned behaviour (extended-TPB). Design/Methods/Approach: We conducted an online survey (N = 222 respondents) using a valid and reliable questionnaire to evaluate people's intention to take the COVID-19 vaccination. A structural equation modeling was performed to demonstrate the impact of religious acceptance (RA), vaccine safety (SF), trust (TS), perceived behavioural control (PBC), attitude towards vaccination (ATT), and subjective norms (SN), on intention (IN) to accept COVID-19 vaccine. Findings: The results show positive relationships of all hypotheses except the correlation between RA and TS. TS becomes a positive determinant of ATT, SN, PBC, and INT, and TS is influenced by SF but not by RA. TS is the key determinant factor of intention to uptake the COVID-19 vaccine. Originality: This study used a proposed extended TPB by adding trust, religious acceptance, and safety as additional components of TPB to predict the intention to participate in COVID-19 vaccination. This study is essential because the vaccine is believed to be the best strategy to deal with virus-related diseases, such as COVID-19. However, there is a lack of information on the multifactor effects of Indonesian people's acceptance of vaccination, especially among Surakarta residents. Practical/Policy implication: This research can be a recommendation for the Indonesian government to elevate public intention to take the COVID-19 vaccine, especially by implementing policies that accentuate people's trust by confirming and publishing information about the vaccine safety.

One of the food-product halalness indicator is the absence of alcohol. In this case, traders as business actors must know about the contamination of khamr and alcohol in food ingredients that are traded so as not to endanger themselves and consumersas a condition when applying for halal certification. Because the content of khamr and alcohol besides endangering health, the Qur'an also clearly forbids them.Therefore this community service aims to increase the knowledge of shop owners around IAIN Surakarta regarding the contamination of khamr and alcohol in food as an effort to prepare for halal certification. This activity is carried out using the socialization method, namely by giving lectures and questions and answers to 10 food stall owners. Activity evaluation is carried out by providing a pre-test and post-test on the topic presented. From this community service activity, there was an increase in knowledge which could be seen from the pre-test and post-test scores, which were respectively 36 and 86. Specifically, the increase in knowledge about the definition of alcohol and khamr was 50%, the rules of the beverage trade. alcohol in Indonesia is 50%, types of alcoholic drinks are 60%, and the law of alcohol and khamr in Islam is 30%.