Glucose is an important carbohydrate which is more absorbed into the bloodstream as glucose and other sugar is changed into glucose in the liver. Blood glucose level is closely related to diabetes mellitus. Diabetes mellitus is a disease that arises in a person which is indicated by the presence of blood glucose levels exceeding normal (hyperglycemia) due to the deficiency of the insulin hormone in the body. The design of this research was using RAL with 24 male rats that divided into 6 treatments which were normal with the giving of Na-CMC 0.5% 1mL/200 gram BB, negative with the giving of Na-CMC 0.5% 1mL/200 gram BB, positive with the giving of glibenclamide of 0.45 mg/kg BB and 3 other treatments by giving catfish biscuit (Formula A, Formula B, and formula C) with 4 replications. All treatments were injected with monohydrate alloxan at a dose of 150 mg/kg BW, except for the normal treatment. The results showed that the formulation of catfish biscuit can lower the blood glucose level of white rats. The composition of biscuit with formula C has the highest decreasing percentage which was 80.20% to the blood glucose level of white rats.

Kondisi sanitasi rumah yang tidak memenuhi syarat kesehatan dapat menimbulkan berbagai macam penyakit dan gangguan kesehatan. Data pemeriksaan rumah sehat di Kelurahan Semanggi diperoleh sebanyak 43,25%. Peran petugas sanitasi dan kepala puskesmas menjadi salah satu yang menentukan keberhasilan cakupan dalam pelaksanaan inspeksi sanitasi di wilayah puskesmas selama 1 (satu) tahun. Berdasarkan survei pendahuluan yang telah dilakukan menunjukkan bahwa masyarakat di kelurahan semanggi jarang mendapatkan info maupun penyuluhan dari petugas yang berkaitan dengan rumah sehat. Penelitian ini bertujuan untuk menganalisis peran petugas terhadap sanitasi rumah di Desa Semanggi Kota Surakarta. Jenis penelitian ini adalah survei analitik dengan menggunakan desain penelitian cross-sectional. Populasi penelitian ini adalah masyarakat yang bertempat tinggal di Kelurahan Semanggi dengan populasi 4.772 rumah dan jumlah sampel 108 rumah, dengan teknik pengambilan proportionate random sampling. Hasil penelitian menunjukkan ada hubungan antara peran petugas kesehatan dengan sanitasi rumah (p=0,000). Petugas kesehatan mempunyai peranan dalam terwujudnya rumah sehat di kelurahan semanggi.

Benzene is a volatile liquid aromatic hydrocarbon. Benzene is also used in industries related to oil processing, one of which is fuel. According to the Agency for Toxic Substances and Disease Register (ATSDR), toxic chemicals contained in oil includes Policyclic Aromatic Hydrocarbons (PAHs), Total Petroleum Hydrocarbon (TPH), benzene, ethylene and toluene. Of all these toxin substances, benzene is the most dangerous chemical and exposure to benzene has a serious impact on human health. As a form of control effort, determining the safe duration of exposure (Dt) for benzene exposure based on the value of RfC (Reference of Concentration) using NOAEL (No Observed Adverse Effect Level) of white mice (Rattus norvegicus) is needed. This study aimed to determine the value of No Observed Adverse Effect Level (NOAEL) of white mice (Rattus norvegicus), safe limits of toxin dosage for the community or Reference of Concentration (RfC), Risk Quontient (RQ) and safe duration of exposure (Dt) in laboratory workers. This was a cross sectional, observational, and descriptive study with 51 samples of PT Pertamina RU IV Cilacap laboratory workers. The object sample used in this study was the air in the work area of the main laboratory section and the petrochemical and gas laboratory of PT Pertamina RU IV Cilacap. The results of this study indicated that safe duration of exposure (Dt) was 19 years; under normal safe duration of exposure for workers. The safe duration of exposure (Dt) can be a reference for the relevant company to consider the workers' working period and reduce the exposure duration with benzene to prevent significant health impact on workers.

Benzene is one of the substances included in the poison of air pollution. The Environmental Protection Agency (EPA) has classified benzene in Group A carcinogens for humans. The widespread use of benzene in the industrial world can have harmful consequences. The amount of exposure workers receive has a negative impact on their health. Workers at the petroleum refinery laboratory are workers at risk of exposure to benzene. The study aimed to measure the safe concentration limit in the Main Laboratory section of PT.