Albumin profile is an important sign of nutritional status as a quality-of life parameter, whereas hypoalbuminemia has been shown to be associated with a high mortality rate for patients with End Stage Renal Disease (ESRD) undergoing dialysis including CAPD. The study was conducted to determine serum albumin levels in patients with ESRD undergoing CAPD therapy. The study was conducted in a cross-sectional manner on ESRD patients who were still actively undergoing CAPD in the outpatient Installation of Dr. Sardjito Hospital Yogyakarta until November 2018. Subjects were examined for serum albumin levels. There were 57 research subjects with the category of albumin levels <3.5 g / dL as many as 19 (33.3%), between 3.5-4.0 g / dL as many as 27 (47.3%) and albumin levels> 4.0 g / dL of 11 (19.3%). There were no significant differences in all age groups, BMI and duration of CAPD. Albumin profile can be an independent parameter of quality of life and even a predictor of mortality in CAPD patients because it does not depend on age group, BMI and length of CAPD

Tulisan ini bertujuan memberikan kontribusi akademis potensi mikroalga Aurantiochytrium dari hutan bakau Indonesia. Tulisan ini mempresentasikan gambaran awal penelitian tentang mikroalga Aurantiochytrium mulai dari teknik isolasi mikroalga dari habitatnya, gambaran produksinya, teknik analisa kualitatif squalene hingga analisa potensi ekonomi dan fungsinya untuk bahan baku adjuvant vaksin. Sebanyak 10 sampel daun bakau diambil dari hutan bakau Raja Ampat, Papua Barat. Teknik isolasi menggunakan metode direct plating method. Setelah aplikasi teknik streaking dari koloni mikroalga yang ada pada sampel ke dalam medium agar, dihasilkan 4 isolat murni.  Produksi awal biomassa berbahan baku mikroalga Aurantiochytrium ditampikan dengan nutrisi glucosa, yeast extract, peptone dan campuran air laut dan aquadest. Analisa kualitatif produk yang dihasilkan menggunakan Kromatografi Lapis Tipis (KLT) menunjukkan hasil positif adanya sqalene pada biomassa hasil kultivasi isolat mikroalga Aurantiochytrium. Squalene dari hasil fermentasi mikroalga Aurantiochytrium telah banyak dikaji sebagai sumber bahan baku alternatif yang ramah lingkungan dan berkelanjutan (sustainable), Beberapa adjuvant vaksin, termasuk vaksin covid-19 menggunakan bahan baku mikroalga Aurantiochytrium untuk menggantikan adjuvant vaksin yang bersumber dari ikan hiu laut dalam. Di masa depan, potensi produk mikroalga Aurantiochytrium akan semakin dibutuhkan di banyak industri nutrisi kesehatan dan kosmetik. Mengingat relevansinya untuk masa depan industri strategis terkait di Indonesia, seyogyanya perlu riset mendalam yang lebih banyak dari isolat mikroalga Aurantiochytrium dari hutan bakau Indonesia.

The purpose of this study is to identify patients at high risk of kidney failure in order to plan treatment. Cross-sectional research method, carried out at the CAPD Outpatient Installation of Dr. Sardjito General Hospital, from October 2018 to November 2018. The results showed three major risk factors for kidney failure, namely hypertension (49.1%), diabetes (17.5%) %) and nephrotoxic (15.8%). The conclusion from the study is hypertension is the highest risk factor for kidney failure.

This study aims to determine the effect of piperine as an antidepressant and the potential to improve brain cognitive function. Researchers conducted a literature review related to piperine's potential for brain work using databases such as PubMed, Google Scholar, Cochrane Library. Search the relevant research literature using the keywords "Piperine in black pepper" or "piperine and brain effects". One of our conclusions is that piperine's cognitive-enhancing effects may occur in part through its cytoprotective and AChE inhibitory effects in the hippocampus.

The healing process of diabetic ulcers is influenced by the nutritional status of the patient, especially the nutritional status of the patient's protein intake.  This study was conducted to determine the relationship between the amount of dietary protein intake of DM patients with the healing process of diabetic ulcers at the Ampel Sehat Inpatient Primary Clinic. This study uses a non-experimental quantitative method with a cross-sectional approach, conducted in May - June 2021 with the research subjects being diabetic ulcer patients who underwent treatment, either outpatient or inpatient stay 1 week with the number of subjects 32 patients aged more than 45 years with this type of male and female, patients with type 2 diabetes mellitus, diabetic ulcers in the leg region, the degree of diabetic ulcers according to Wagner with a score of 1-3, and the patient has full consciousness. Data collection on the amount of dietary protein intake of DM patients was obtained through interviews and questionnaires. The data were analyzed by using the chi-square correlation test or Fisher's exact. The research subjects on average did not have sufficient daily protein intake and did not experience the healing process of their diabetic ulcers. The relationship between the amount of dietary protein intake in DM patients and the healing process of diabetic ulcers was found. This study concludes that there is a relationship between the amount of dietary protein intake of DM patients with the healing process of diabetic ulcers at the Ampel Sehat Inpatient Primary Clinic. Abstrak Proses penyembuhan ulkus diabetikum dipengaruhi oleh status gizi pasien, terutama status gizi asupan protein pasien. Penelitian ini dilakukan untuk mengetahui hubungan antara jumlah asupan protein diet pasien DM dengan proses penyembuhan ulkus diabetikum di Klinik Pratama Rawat Inap Ampel Sehat. Penelitian ini menggunakan metode kuantitatif non eksperimental dengan pendekatan cross sectional, dilakukan pada bulan Mei – Juni 2021. dengan subjek penelitian adalah pasien ulkus diabetikum yang menjalani pengobatan, baik rawat jalan maupun rawat inap 1 minggu dengan jumlah subjek 32 pasien berusia lebih. dari 45 tahun dengan tipe ini pria dan wanita, pasien diabetes mellitus tipe 2, ulkus diabetik di daerah kaki, derajat ulkus diabetik menurut Wagner dengan skor 1-3, dan pasien memiliki kesadaran penuh. Pengumpulan data jumlah asupan protein diet pasien DM diperoleh melalui wawancara dan kuesioner. Analisis data menggunakan uji korelasi chi-square atau Fisher's exact. Subyek penelitian rata-rata tidak memiliki asupan protein harian yang cukup dan tidak mengalami proses penyembuhan ulkus diabetikumnya. Ditemukan hubungan antara jumlah asupan protein diet pada pasien DM dengan proses penyembuhan ulkus diabetikum. Penelitian ini menyimpulkan bahwa ada hubungan antara jumlah asupan protein diet pasien DM dengan proses penyembuhan ulkus diabetik di Klinik Pratama Rawat Inap Ampel Sehat         This is an open access article under the CC–BY-SA license. _______