What is already known on this topic? It is estimated that 13 million people in the United States have latent tuberculosis infection (LTBI). This large number of potential LTBI cases poses a challenge for successful tuberculosis control and elimination. What is added by this report? We examined a novel, collaborative care model using community pharmacies as additional access points for LTBI treatment for patients using combination weekly therapy with isoniazid and rifapentine and directly observed therapy for 12 weeks. What are the implications for public health practice? High completion rates and safe administration of LTBI treatment can be achieved in the community pharmacy setting.

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