Hydrogen gas turbines and burners need high attention and their appropriate realization, yet during their design, can lead important benefits for the whole sector. Realizing the best design, the first time, reduces reworks and requests of design changes from the manufacturing departments. In this field, Knowledge Based Engineering is a good strategy for embedding, in an automatic way, experts’ knowledge into CAD models during the design of a component. It enables a reduction of human errors and costs in several design tasks and improving the final quality of a component model. With these premises, the aim to the study is to lead improvements and appropriate actions in the design and re-configuration of hydrogen power generation systems (i.e. gas turbines and burners) by means of KBE, leading improvements yet in this early phase of the global race for hydrogen. A systematic literature review is carried out to explore the current state of art for the application of KBE for the design of turbines and burners in different industrial sectors. Evidences from the practice are collected in a structured classification and elaborated and summarized for application in the design of gas turbines and burners for the hydrogen production.