African leaves (Vernonia amygdalina Del) is a plant that can be used as a medicinal plant because it contains flavonoid compounds that are effective as natural antioxidants that can suppress free radicals. The purpose of this study was to determine the antioxidant activity of the purified extract of Vernonia amygdalina Del. Antioxidant activity test of purified extract of Vernonia amygdalina Del leaves against 1,1-diphenyl-2-picrylhydrazil (DPPH) was measured with a UV-Vis spectrophotometer at a wavelength of 516nm using Vitamin C as a comparison. The results of the non-specific parameters of Vernonia amygdalina Del leaf Simplicia were drying shrinkage of 0.79±0.02%; water content of 7.33±2.08%; water-soluble essence content of 20.5±1.73 %; and ethanol of 14.5±4.35 %. The results of purified extract screening of Vernonia amygdalina Del leaves, contained chemical compounds, namely the class of flavonoid compounds, tannin compounds, steroid compounds, and saponin compounds. Testing for flavonoids using the Thin Layer Chromatography method on the purified extract contained two spots with Rf values of 0.68 and 0.5 while in quercetin there was one spot with an Rf value of 0.68, thus the purified extract of Vernonia amygdalina Del leaves contained flavonoids. Vernonia amygdalina Del leaf purified extract has a very strong antioxidant activity with an IC50 value of 13.54±0.10 µg/mL. The results showed that the purified extract of Vernonia amygdalina Del leaves had very strong antioxidant activity.

Tanaman obat keluarga merupakan pemanfaatan tanaman berkhasiat obat yang terdapat di halaman, pekarangan atau di kebun dalam upaya memenuhi kebutuhan obat keluarga. Beberapa contoh tanaman obat keluarga adalah Curcuma domesticae L., Greater Galangal, Celery yang mengandung senyawa flavonoid sebagai senyawa utama yang bertanggung jawab akan aktivitas biologis dan menunjukkan sifat anti-inflamasi, antivirus, anti bakteri, antioksidan, dan aktivitas nematosidal. Pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan di Graha Yatim Dhuafa Kertawinangun akan manfaat tanaman obat keluarga mudah ditemukan di pekarangan rumah. Metode pada pengabdian ini menggunakan instrument lembar post test dan pre test untuk mengevaluasi daya tangkap anak sebelum dan sesudah dilakukannya penyuluhan oleh pihak mahasiswa yang kemudian dinilai dan dibuat grafik dari nilai tersebut. Setelah dilakukannya pengolahan nilai, diketahui nilai rata-rata pre test adalah 60,5 sedangkan nilai ratarata post test meningkat sebanyak 20 poin yaitu 80,5 yang menunjukkan tercapainya pelaksanaan edukasi dan sosialisasi mengenai tanaman obat keluarga. Dari hasil tersebut dapat dipastikan adanya peningkatan pengetahuan pada anak-anak tersebut mengenai Tanaman Obat Keluarga serta pemanfaatannya.

Brotowali (Tinospora cordifolia) plants are usually used for various kinds of treatment it is often used as a febrifuge, brotowali stems are proven to contain flavonoid compounds that have benefits in the treatment of various diseases, one of which is analgesic. This purpose is to determine the effectiveness of analgesics on male Swiss mice induced by acetic acid from the ethanol extract of brotowali stem (EETC) doses of 100 mg/Kg BW, 200 mg/Kg BW, and 400 mg/Kg BW. Brotowali stem extraction using maceration method with 70% ethanol solvent. EETC was tested by phytochemical screening and TLC to determine the content of active compounds. The test animals used Swiss male mice, the treatment group was divided into 5, negative control group, positive control, and the dose groups were 100 mg/kg BW, 200 mg/kg BW, and 400 mg/kg BW. Testing is done by the writhing test method. Induction of pain stimuli using acetic acid, the number of mice writhing every 10 minutes for 1 hour, and the percentage of analgesic power. Research shows the yield of EETC is 16.35%. The percentage of analgetic power of dose I was 39%, dose II was 47% and dose III was 56% less than the percentage of analgesic power of methampyrone dose of 65 mg/KgBB which was 64%. Conclusion EETC doses of 100 mg/kg BW, 200 mg/kg BW, and 400 mg/kg BW have analgesic activity equivalent to methampyrone at a dose of 65 mg/kg BW, with the largest percentage of analgesic protection at a dose of 400 mg/Kg BW of 56%.

Penyakit infeksi merupakan jenis penyakit yang paling banyak diderita oleh penduduk di negara berkembang, termasuk Indonesia. Salah satu penyebab penyakit infeksi adalah bakteri. Penyakit infeksi di Indonesia kebanyakan diobati dengan menggunakan antibiotik. Alternatif untuk mengobati infeksi yaitu dengan memanfaatkan bahan-bahan alami dari tanaman obat.Salah satu tanaman yang berpotensi sebagai obat herbal adalah tanaman daun suji (Pleomele angustifolia N. E. Brown). Tujuan dari penelitian ini adalah untuk mengetahui apakah ekstrak etanol daun suji (Pleomele angustifolia N. E. Brown) pada konsentrasi 10%, 20%, 40% dan 80% dapat menghambat dan bagaimana pengaruh peningkatan konsentrasi ekstrak etanol terhadap daya hambat pertumbuhan bakteri Staphylococcus aureus. Untuk itu dilakukan penelitian dengan menggunakan metode uji daya hambat difusi cetak lubang ekstrak etanol daun suji (Pleomele angustifolia N.E.Brown) terhadap bakteri Staphylococcus aureus. Daun suji yang dijadikan ekstrak kental dengan konsentrasi 10%, 20%, 40%, dan 80%. Hasil penelitian yang didapat menunjukkan hanya ekstrak etanol daun suji pada konsentrasi 80% saja yang dapat menghambat pertumbuhan bakteri Staphylococcus aureus dengan zona hambat 1,42 mm. Kontrol positif yang dijadikan pembanding adalah amoxicillin injeksi 0,001% membentuk diameter rata-rata 2,23 mm.

Many problems are caused by the use of synthetic chemical drugs, so looking for other alternatives for treating diabetes is using materials from nature. Research on some natural ingredients showed that ethanol extract of kersen leaf (Muntingia calabura L.) contains flavonoids that allegedly have the effect of lowering blood glucose levels. This study aims to determine the effect of ethanol extract of kersen leaf (Muntingia calabura L.) In lowering blood glucose levels in male mice (Mus musculus). The antidiabetic effectiveness test was performed using 25 male mice divided into 5 groups: positive control group (glibenclamide), negative control group (Na CMC), ethanol extract group of cherry leaf (Muntingia calabura L.) 6 mg dose / 20 g bb mice, 9 mg/ 20 g bb mice, and 12 mg / 20 g bb mice. Blood glucose measurement at minutes 0, 30, 60, 90, 120 was then analyzed using a one way, anova statistical test with 95% confidence level then continued with least significant different (LSD) test. [A1] The results showed that the most effective dose to decrease blood glucose level in male mice was ethanol extract of kersen leaf (Muntingia calabura L.) Dose 12 mg / 20 g bb