Brachycephalic syndrome (BS) in dogs is characterized by the combination of primary and secondary upper respiratory tract abnormalities and may result in significant upper airway obstruction. It can trigger inspiratory dyspnea, culminating in secondary respiratory distress, soft tissue edema, upper airway obstruction, turbulent airflow, inspiratory noise, and even death. These changes lead to increased resistance of the air passages, which can cause elevation of pulmonary pressure and clinical manifestations attributable to pulmonary hypertension. The consequence is right-sided cardiac remodeling (Cor pulmonale) with possible progression to right congestive heart failure. To investigate the effects of BS on the cardiovascular system, 28 animals were recruited for a prospective study and assigned to either the Brachycephalic Group (BG), composed of 22 French bulldogs with BS or the Control Group (CG), which was composed of 6 healthy Beagle dogs. All animals underwent a detailed physical examination, as well as laboratory analyses, electrocardiography, echocardiography, chest radiography and indirect measurement of systemic arterial blood pressure. The most relevant finding was a lower PaO2 (90.6±12.9mmHg) in BG as compared to CG (104.9±5.2), (p≤0.05), possibly attributable to hypoventilation due to anatomical alterations.
O carcinoma espinocelular, ou carcinoma epidermóide, é uma neoplasia maligna de células escamosas. Possui crescimento rápido nas células epidérmicas, sendo comumente encontrado na espécie equina, em regiões como pênis e prepúcio, tendo maior predileção por animais de idade avançada e não castrados. O diagnóstico diferencial é baseado em fatores como sintomatologia clínica e citologia, assim como no exame histopatológico da lesão. Dentre as possibilidades para acometimento em pênis, a remoção cirúrgica da lesão, ou seja, a penectomia, é o tratamento de eleição para o carcinoma espinocelular, pontuando que, nessa neoplasia, é comum haver casos de recidiva . Este trabalho relata um caso de carcinoma epidermóide em um equino sem raça definida (SRD) atendido no hospital veterinário (HV) da Faculdade Dr. Francisco Maeda e descreve a técnica cirúrgica utilizada para o tratamento.
The purpose of this study was to evaluate the effects of lumbar myelography on subarachnoid pressure, cardiorespiratory parameters and pressure-volume index in sheep. Eight sheep were evaluated. The animals were submitted to puncture of the cisterna magna for monitoring of subarachnoid pressure (SaP). Lumbar myelography was performed through applying Iohexol (0.4mL/kg). ToC, PAS, PAD, MAP, InspISO, FeISO, SaP and CPP were recorded immediately after anesthetic stabilization (M0), during lumbar puncture (M1), and two, four and six minutes after contrast application (M2, M3 and M4, respectively). Blood pressure initially increased, then decreased, returning to basal level, similarly observed for InspISo and FeISo. The SaP rose initially thereafter remaining stable. Despite of the effect on subarachnoid pressure, lumbar myelography can be considered safe in sheep.
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