A novel route was successfully developed for the synthesis of new synthons, orthoamino formyl quinoline (heterocyclic orthoaminoaldehyde) and utilized for the synthesis of series of benzonaphthyridines by Friedländer condensation reactions with benzoylacetonitrile. The benzonaphthyridines synthesized were further studied for their fluorescence properties. Copyright © 2010 John Wiley & Sons, Ltd.

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Novel and Efficient Synthesis of Pyrimidine Derivatives. -A novel two-step approach to pyrimidines (IV) via the easily accessible formamidine precursor (I) is presented. -(GHAGARE, M. G.; BIRARI, D. R.; SHELAR, D. P.; TOCHE, R. B.; JACHAK*, M. N.; Synth. Commun. 40 (2010) 11, 1580-1587,

in Wiley InterScience (www.interscience.wiley.com).Vilsmeier-Haack formylation of acetonitrile using dimethylformamide and phosphorus oxychloride leading to a novel intermediate, N-((E)-3-(dimethylamino)-2-formylacryloyl)formamidine 2 and its utility in the synthesis of pyrimidine-fused heterocycles such as pyrazolo[1,5-a]pyrimidines and triazolo [1,5-a]pyrimidine is reported.

A rapid and efficient method for the synthesis of novel dipyrazolo[3,4-b:3',4'-d]pyridines (DPP) from pyrazolo[3,4-b]pyridine was successfully developed. The DPP derivative was further N-alkylated (6, 8) as well as N-linked with amino acids (13) and their photophysical properties were studied along with N-aryl DPP 4 and observed that the chromophores at C(4) position in the aryl ring changed the absorption and emission lambda(max).