This studied aims to explained the effect of the variables of inflation, consumption expenditure, capital formation, foreign direct investment, and trade openness on gross domestic product ASEAN countries from 1996 – 2018. This research used a panel regression analyzed method to test the data in getting decisions. The t-statistic test results showed that consumption expenditure, capital formation, foreign direct investment, and trade openness significantly influence the direction of a positive relationship to gross domestic product. However, inflation showed a negative direction and had a significant effect on the gross domestic product so that if there is increased inflation it will reduce gross domestic product. The government can formula a single-digit policy so that there is no decline in the gross domestic product of ASEAN countries.