Masticatory system is a complex functional unit of the body primarily responsible for mastication, speech and deglutition process. Temporomandibular disorders (TMD) is used to describe all functional disturbances of the masticatory system. The etiology of TMD is multifactorial, such as occlusal disharmony and emotional stress. The relationship between occlusion and TMD has been highly debated in dentistry, one of the occlusal guidance, group function, and balanced occlusion. However, studies about the relationship of occlusal schemes and the occurrence of the TMD are still limited and remained controversial. Objective: To investigate the relationship of occlusal schemes with the occurrence of TMD. Methods: A cross-sectional study was conducted at the Faculty of Dentistry, Universitas Indonesia. A total of 127 students were included in this study. Subjects were examined based on Clinical Helkimo Index and divided into TMD and non-TMD groups. Subjects were categorized as non-TMD group if the value of clinical Helkimo index was 0 and as TMD group when the value ranged between 1-25. Results: Balanced occlusion schemes has a greater risk of TMD occurrence with odds ratio p=0.021). Conclusion: Balanced occlusion has a ABSTRAK Hubungan skema oklusal dengan terjadinya kelainan temporomandibula. Sistem mastikasi merupakan unit kompleks fungsional tubuh yang bertanggung jawab untuk pengunyahan, bicara, dan proses deglutasi. Temporomandibular Disorders (TMD) digunakan untuk menggambarkan semua gangguan fungsional dari sistem mastikasi. Etiologi TMD bisa disebabkan berbagai faktor, seperti ketidakharmonisan oklusal dan stres emosional. Hubungan antara oklusi dan TMD diperdebatkan dalam kedokteran gigi, salah satu faktor oklusal fungsi kelompok, dan oklusi seimbang. Namun, studi tentang hubungan skema oklusal dan terjadinya TMD masih terbatas dan tetap kontroversial. Tujuan: Untuk menyelidiki hubungan skema oklusal dengan terjadinya TMD. Metode: Studi potong lintang dilaksanakan di Fakultas Kedokteran Gigi, Universitas Indonesia. Subjek penelitian berjumlah 127 mahasiswa. Subjek diperiksa berdasarkan Indeks Klinis Helkimo dan dibagi menjadi kelompok TMD dan non TMD. Subjek dikategorikan sebagai kelompok non-TMD jika nilai Indeks Klinis Helkimo bernilai 0 dan kelompok TMD jika nilainya antara 1-25. Hasil: Skema oklusi yang seimbang memiliki risiko yang lebih besar untuk terjadinya TMD dengan nilai odd ratio 5,6 dengan p=0,021). Simpulan:Key words: occlusal schemes, temporomandibular disorders PENDAHULUAN Okeson menggunakan istilah temporomandibular disorders (TMDs) untuk seluruh gangguan fungsional dalam sistem pengunyahan. Etiologi gangguan sendi temporomandibula adalah faktor-faktor yang dapat menimbulkan pembebanan yang melebihi kapasitas adaptasi sendi, baik beban sesaat yang ekstrim maupun beban berulang. Umumnya ditandai oleh rasa nyeri pada otot-otot mastikasi dan sendi saat palpasi,
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