In contemporary era the urologists have several options for treating reno uretheral stones in the range of 5- 20mm. Of that range, this study makes a comparison between ESWL and ureteroscopic holmium laser lithotripsy in the treatment of reno uretheral stones. Acording of that ureteroscopy and ESWL such as a methods of treatment are invasive procedures, still there is controversy which of them is more acceptable for treating reno ureteral stones disease. Generally, the total cost, the procedural time and analgesia requirements and were noticeably variant. Additionally, gross hematuria and renal colic were more frequent with ESWL procedure, while the voiding symptoms show more frequency with ureteroscopy procedure.

The efficiency and safety of the Holmium Laser has made this method of treatment a versatile multi-purpose instrument for use in the endoscopic treatment for variety of urologic disorders, in particular urinary stones. According to progressive development of new technologies - current endourologic laser lithotripsy applications, for treatment of urinary stone disease has a substantial role for urologist practitioner.