Background: Coronavirus disease-19 (COVID-19) is an infectious disease with high morbidity and mortality rates. Indonesia had reported a 2.8% of mortality rate up to June 2021. A strategy to control the virus spreading is by vaccination. The Indonesian Food and Drug Monitoring Agency had approved the use of CoronaVac, an inactivated virus vaccine developed by Sinovac. Most adverse events following immunization (AEFI) for CoronaVac are mild, and the most common symptoms are injection-site pain, headache, and fatigue. Neurovascular adverse events, including thrombosis or ischaemic stroke after receiving CoronaVac have not previously been reported. Correspondingly, we reported three patients with an Acute Ischaemic Stroke (AIS) after the administration of CoronaVac in our hospital.

Background COVID-19 increases the risk of acute ischemic stroke. The objective of this study is to identify the risk factors, comorbidities, and outcomes in COVID-19 patients with acute ischemic stroke at University of Indonesia Hospital. Results The clinical condition of COVID-19 patients with ischemic stroke is more severe for patients older than 55 years (p < 0.05), patients at the critical COVID-19 clinical stage, and patients with atrial fibrillation (p < 0.05). The level of C-reactive protein (CRP) more than 60 mg/L correlated with the outcome of the patient as well. Conclusion The study concluded that, age, COVID-19 clinical degree, and atrial fibrillation significantly affect the outcome in COVID-19 patients with stroke.

iskemik akut dalam mendapatkan terapi secara segera agar luaran yang didapatkan efektif dan maksimal. RSUPN Dr. Cipto Mangunkusumo dan RS Universitas Indonesia merupakan dua rumah sakit pendidikan dengan latar belakang, sumber daya, sarana prasarana, dan kondisi yang berbeda dalam penerapan sistem code stroke. Tulisan ini membandingkan sistem code stroke pada kedua rumah sakit meliputi tenaga kesehatan IGD, biaya dan cakupan fasilitas, pemeriksaan pencitraan diagnosis stroke, pengusul sistem code stroke, ruang observasi, ketersediaan lab kateterisasi, dan komunikasi tim sistem code stroke. Sistem code stroke dapat diterapkan pada berbagai rumah sakit dengan menyesuaikan kondisi rumah sakit masing-masing dengan cara memaksimalkan kelebihan yang ada untuk melengkapi kekurangan dari rumah sakit tersebut. Kata kunci: Code stroke, rumah sakit, stroke iskemik, trombektomi, trombolisis