In order to achieve the catalytic oxidation of the low concentration SO2 flue gas in SNOX process, screen out the appropriate type of V2O5 catalyst for high-efficient transformation of the low concentration SO2. In order to provide foundation for reaction progression design, calculate the reaction depth of the process condition through the reaction thermodynamics analysis. According to the technological factors of affecting the effect of catalytic oxidation, investigate the reaction temperature, the space velocity and the mole ratio between O 2and SO2 on the SO2 transformation. Based on the experimental results, we did the reaction kinetics calculation. Above theoretical and experimental results provide the necessary technical parameters for designing catalystic oxidation of the low concentration SO2 in SNOX process.