This paper examines the relationship between the occupational stress of employees in small and medium enterprises (SMEs) and their intentions to leave the organization. A sample of 154 employees from SMEs completed written questionnaires. The responses from the sample are used to test the hypotheses that job satisfaction, affective commitment, and perceived organizational support (POS) will mediate the relationship between stress and intention to leave. The results of the regression analyses indicate that POS fully mediates the relationship between stress and intention to leave, while job satisfaction and affective commitment are partial mediators of the aforementioned relationship. The implications of the findings for managementparticularly those in SMEs-are discussed, as are the limitations of the research and directions for future research in this domain.