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The aim was to study the effect of normobaric hypoxia on biochemical parameters to assess homeostatic changes caused by mental work.Materials and methods: 90 highly qualified athletes of various specializations took part in the scientific observation. Athletes performed psychophysiological tests to determine mental performance under normal conditions and under the influence of normobaric hypoxia.Results: the concentrations of lactate (La), glucose (Glu), cholesterol (Chol), and triglycerides (Trigl) in the blood were measured four times at different stages.Conclusions: it was shown that athletes after staying in NH conditions significantly increased the La, Glu, Chol and Trigl indices, which indicates the mobilization of energy resources and an increase in anaerobic processes in response to NH exposure. Re-performance of mental work after exposure to NH was associated with a marked decrease in the concentration of Glu, Chol, and Trigl, along with a slight increase in the concentration of La after normobaric hypoxic exposure, there are significant changes in the bioenergetic profile in athletes.

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