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The interrelation among chemical compositions, structure, and heating properties of cobalt doped magnetite nanoparticles (CoxFe3−xO4 NPs) for their potential hyperthermia application.

Nanosized mixed ferrite Mn 0.3 Zn 0.7 Fe 2 O 4 was prepared by a hydrothermal method at pH 11 and 180°C. XRD analysis showed that the material had the characteristic spinel structure with average particle size 14 nm. The real part of the AC susceptibility clearly proved the ferrite had spin glass like behavior. Magnetic inductive heating studies were performed at 236 kHz with magnetic field amplitude 50-80 Oe. The specific absorption (SA) was investigated by use of linear response theory. The experimental results were in good agreement with theoretical predictions. Moreover, the intrinsic loss power (ILP) was calculated from SA values. It is believed that Mn 0.3 Zn 0.7 Fe 2 O 4 nanoparticles with a high ILP will be useful for in situ hyperthermia treatment of cancer.

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