The aim of this study is to compare the efficiency of Platelet-rich plasma (PRP) in the treatment of acute lesions and chronical disease of bones, joints and nerves from forearm, wrist and hand. Material and Methods: articles published in English between 2008 and 2018 from medical literature were selected. Results: when it comes to acute lesions three articles were found; one about the using of PRP in distal radius fractures and the two about the infiltration of PRP in the complete neurotmesis of radial nerve or in digital nerve incomplete section. In chronic conditions only one article about trapeziometacarpian (TMC) osteoarthritis (OA) was found, and three articles about a median nerve compression in carpal tunnel syndrome (CTS). Conclusions: 1.The medical literature contains few publications regarding the efficiency of PRP in treatment of traumatic lesions and chronic disease of forearm, wrist and hand. 2. In chronic conditions the favorable outcomes after the PRP injection are obtained only in the first stage of the disease, in advanced stages the surgical treatment is mandatory.

Introduction. The goal of this study was to compare the two surgical procedures (arthroscopic versus open surgery) in the treatment of Kienböck disease (KD) and all therapeutic options depending on the stage of disease.Materials and Methods. Various electronic databases were used to search for articles on this topic. This review aims to evaluate and summarise the various surgical interventions and their outcomes in KD.Results. Many treatments for KD are described, various surgical options are available based on the stage of disease. The surgical procedure including radial shortening osteotomy, capitate shortening osteotomy, total wrist arthrodesis, proximal row carpectomy, scapho-trapezio-trapezoid arthrodesis, vascularized bone grafting, excisional arthroplasty are the most commonly used. In the study there were included a number of 190 patients in different stages (Lichtman) of KD. They have undergrove to surgical interventions (arthroscopic and open surgery) by following the same things in each group; decreasing pain, increasing range of motion (ROM) and grip strength, also earlier return to unrestricted daily activities. Patients were follow-up for a long period (between 1year and 10 years postoperative). Conclusions. 1.For each stage of KD, there are several therapeutic options.2. Preoperative arthroscopic evaluation of cartilage damage can inform treatment decisions. Arthroscopic surgery resulted in shorter operating time, shorter hospital stay and earlier return to unrestricted daily activities.