For each strategy the following points were addressed: the information to be given to the consultee, the procedure and the indications. In addition, the committee's opinion about BRCA1 and BRCA2 mutation screening is that population-based, or even large-scale, implementation are not justified. Although no scientific evidence is available, the committee feels that specific management is indispensable and advocates the use of defined and evaluated procedures, and participation in clinical trials.

Aims-To determine functional results after unilateral and bilateral cataract surgery in children with diVerent aphakic optical correction. Methods-In this retrospective study, we evaluated visual acuity and binocular vision in 107 children who underwent cataract surgery during the 10 year period from 1985 to 1995. Aphakia was corrected by an intracapsular intraocular lens (IOL), spectacles or contact lenses. Results-Mean visual acuity was >20/40 (<0.3 log MAR) with normal binocular vision in 58 children over 7 months of age operated on for bilateral cataracts. Pseudophakic eyes regained visual acuity >20/63 (<0.5 log MAR) more often (90%) than aphakic eyes (46%) (p<0.001). Binocular vision was also achieved more often after IOL implantation (p<0.001). Visual outcome of early bilateral cataracts was less satisfactory in children with abnormal foveolar function. For 49 children who had surgery for unilateral cataracts, prognosis was poor when surgery was performed before the age of 7 months. For cataract surgery in older children (>7 months) mean visual acuities were better with IOL implantation (p<0.05). Conclusion-Cataract surgery with unilateral and bilateral IOL implantation can provide a beneficial eVect on final visual outcome in children who are operated on before abnormal foveolar function develops.

Our results suggest that fadenoperation of MR is an option to treat esotropias that disappear under anesthesia. The retroequatorial strapping we use seems safer than classical fadenoperation. We believe that the position of the eyes under GA should be considered for the surgical approach of esotropias.