TC‐E 5003 increases the expression of UCP1 in primary iWAT cells.
TC‐E 5003 activates the downstream molecules of PKA signaling.
Thermogenic effects of TC‐E 5003 are PRMT1‐ and β‐adrenergic receptor‐independent.
TC‐E 5003 potently works in human SQ adipocytes isolated from multiple donors.
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