The aim of this study was to analyze the long-term outcomes of endodontic microsurgeries in a cohort and identify their association with prognostic factors. A cohort of endodontic microsurgeries followed up periodically with complete clinical and radiographic records for at least 5 years were reviewed retrospectively. Their survival and healing status and profile characteristics were analyzed by Pearson chi-square test and logistic regression (α = 0.05) to identify prognostic factors that influenced outcomes. Of 652 cases in the cohort, 225 (34.5%) were included. The mean follow-up period was 90.4 months (range, 60–168 months). The long-term success rate was 80.5%, and the 5-year survival rate was 83.5%. Logistic regression showed higher success in anteriors compared to molars (OR = 5.405, (95% CI, 1.663–17.571; p = 0.005)) and in teeth with crown restorations (OR = 10.232, (95% CI, 3.374–31.024; p < 0.001)). Conversely, lower success was found in teeth with periodontal disease (OR = 0.170, (95% CI, 0.032–0.900; p = 0.037)) and maxillary sinus involvement (OR = 0.187, (95% CI, 0.035–0.994; p = 0.049)). Endodontic microsurgery has a highly favorable long-term outcome. Tooth position, crown restoration, periodontal disease, and maxillary sinus involvement were identified as main prognostic factors.

Research issue on 2D coordination networks is moving toward practical applications. Recent developments in such 2D networks include exciting advances in efficient single-crystal-to-single-crystal (SCSC) functionality. This account highlights advances in various 2D coordination networks as SCSC porous platforms for dye inclusion as an energy transfer system, template for x-ray crystal structure determination of various liquids, polymorphism materials, efficient heterogeneous catalysts, separation of o-, m-, and m-xylene, sensing via interlayer-tuning, recognition and reservoir of unstable diiodomethane, chiral recognition in SCSC mode.The key point of their utility is not only the construction of recyclable tolerant 2D networks but also channel-tuning for inclusion of targeting guest molecules. The targeting guest molecules, which are appropriate with the polarity, shape, and size of 2D pores, can, instead of simple organic solvates, be incorporated into the porous crystals in SCSC mode, thus giving rise to recyclable tolerant host-guest systems in the crystalline state.

We prepared the monomer PCDA-HP composed of 5-hydroxy-N 1 ,N 3 -bis(pyridin-2-ylmethyl)isophthalamide (HP) as a cadmium ion tweezer and then polymerized them to form a polydiacetylene (PDA)-based sensor (PDA-HP), which displayed selective and sensitive colorimetric and fluorometric change upon addition of a cadmium ion (Cd 2+ ) at both pH 7.4 and 6.8. The PDA-HP polymer was highly selective for Cd 2+ over other metal ions with colorimetric change. In addition, the PDA-HP chemosensor also showed a red fluorescence change in the presence of Cd 2+ at both pH 7.4 and 6.8. Naked-eye detection of Cd 2+ was accomplished in an aqueous solution through a PDAbased sensor system. Finally, the lowest energy structure of an HP chelator was obtained by the crystal structure and density functional theory (DFT) calculations.

A pair of chiral 2D enantiomeric sheets were constructed using AgPF6 with a pair of chiral tridentate ligands. The differential pulse voltammetric (DPV) technique was found to be an effective tool for enantio-recognition of l- and d-histidines.

To date, a large number of photosensitizers (PS) have introduced heavy atoms to improve the ISC process and 1O2 generation. However, they often show low efficiency in hypoxic conditions, aggregate states, and turn-off PDT in the dark. Besides that, the toxicity of heavy metals is also concerned. Therefore, we developed lysosome-targeted heavy-metal-free PS (3S and 4S) based on thionated naphthalimide for hypoxic cancer photodynamic therapy (PDT), not only under white light but also in the dark via thermal-induced 1O2 generation. AIEgen (3O and 4O) were prepared for studying the PDT action of PSs (3S and 4S) in lysosome and aggregate state. We also examined the photophysical properties of AIEgen (3O and 4O) and PS (3S and 4S) by UV–vis absorption, fluorescent emission spectra, and theoretical calculations.